Impact of ECMO on long-term outcomes in children with severe respiratory distress
ASCEND (ARDS in Children and ECMO initiation strategies impact on Neuro-Development)
This study looks at how using a special breathing machine called ECMO helps kids with serious lung problems recover and grow over time, so parents can better understand the best ways to treat their children when they are very sick.
Quick facts
| Grant type | R01 grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | University of Michigan at Ann Arbor NIH-funded |
| Lab location | 1 site (Ann Arbor, United States) |
| Project ID | NIH-10867477 on NIH RePORTER |
What this research studies
This research investigates how extracorporeal membrane oxygenation (ECMO) affects the long-term health and development of children suffering from severe pediatric acute respiratory distress syndrome (PARDS). By comparing outcomes in children who received ECMO to those who did not, the study aims to determine the best timing for ECMO initiation to improve survival and quality of life. The research utilizes data from a large clinical trial and an ECMO registry to analyze the effects of different treatment strategies. Parents of critically ill children may find this research relevant as it seeks to clarify treatment options for severe respiratory conditions.
Who could benefit from this research
Good fit: Ideal candidates for this research are children aged 0-11 years who are experiencing severe pediatric acute respiratory distress syndrome.
Not a fit: Patients who are not critically ill or do not have severe respiratory distress may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to improved treatment protocols for children with severe respiratory distress, enhancing their chances of survival and quality of life.
How similar studies have performed: Previous research has shown promising results in understanding ECMO's impact on pediatric patients, but this specific approach is novel in its focus on long-term outcomes.
Where this research is happening
Ann Arbor, United States
- University of Michigan at Ann Arbor — Ann Arbor, United States (Active)
Researchers
- Principal investigator: Barbaro, Ryan Pasquale — University of Michigan at Ann Arbor
- Study coordinator: Barbaro, Ryan Pasquale
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.