Impact of early exposure to certain chemicals on weight and heart health in teens
Early life organophosphate ester (OPE) exposures and adiposity and cardiometabolic health during adolescence
This study is looking at how exposure to certain chemicals found in everyday household products during childhood might affect weight gain and heart health in teenagers, helping us understand if these chemicals play a role in rising obesity and heart issues among young people.
Quick facts
| Grant type | R01 grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | University of Nevada Las Vegas NIH-funded |
| Lab location | 1 site (Las Vegas, United States) |
| Project ID | NIH-10894052 on NIH RePORTER |
What this research studies
This research investigates how exposure to organophosphate esters (OPEs), commonly found in household products, during early life affects weight gain and heart health in adolescents. The study will analyze biological pathways that may be disrupted by these chemicals, potentially leading to obesity and related health issues. By examining data from children and adolescents, the research aims to identify patterns and correlations between OPE exposure and various health metrics, such as body mass index (BMI) and cholesterol levels. The findings could provide insights into how environmental factors contribute to the rising rates of obesity and cardiometabolic diseases in young people.
Who could benefit from this research
Good fit: Ideal candidates for this research include children and adolescents who have been exposed to organophosphate esters and are experiencing weight gain or related health concerns.
Not a fit: Patients who have not been exposed to organophosphate esters or who are not within the age range of 0-20 years may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to better understanding and prevention strategies for obesity and heart health issues in adolescents.
How similar studies have performed: Previous research has indicated that environmental exposures can significantly impact obesity and metabolic health, suggesting that this study builds on established findings.
Where this research is happening
Las Vegas, United States
- University of Nevada Las Vegas — Las Vegas, United States (Active)
Researchers
- Principal investigator: Vuong, Ann — University of Nevada Las Vegas
- Study coordinator: Vuong, Ann
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.