Impact of DHEA and exercise on fat in bone marrow for older women
Effects of DHEA and exercise on bone marrow fat in postmenopausal women
This study is looking at how the hormone DHEA and exercise can help improve bone health in postmenopausal women by reducing fat in the bone marrow and increasing bone density, so if you're a woman in this stage of life, you might find it helpful for keeping your bones strong and preventing fractures.
Quick facts
| Grant type | R01 grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | University of Colorado Denver NIH-funded |
| Lab location | 1 site (Aurora, UNITED STATES) |
| Project ID | NIH-10651634 on NIH RePORTER |
What this research studies
This research investigates how the hormone dehydroepiandrosterone (DHEA) and exercise affect bone marrow fat and bone density in postmenopausal women. Participants will engage in a clinical trial that combines DHEA therapy with exercise to assess changes in bone health. The study aims to provide insights into alternative treatments for improving bone strength and reducing fracture risk in older women. Advanced imaging techniques will be used to analyze the effects on bone marrow fat and overall bone health.
Who could benefit from this research
Good fit: Ideal candidates for this research are postmenopausal women experiencing bone loss.
Not a fit: Patients who are not postmenopausal or those with other significant health conditions affecting bone health may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to new, low-cost treatment options for improving bone health in postmenopausal women.
How similar studies have performed: Previous research has shown promising results in using DHEA and exercise to improve bone health, suggesting this approach may be effective.
Where this research is happening
Aurora, UNITED STATES
- University of Colorado Denver — Aurora, United States (Active)
Researchers
- Principal investigator: Jankowski, Catherine M — University of Colorado Denver
- Study coordinator: Jankowski, Catherine M
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.