Impact of chemical mixtures on children's brain health

Effect of complex mixtures on oxidative stress and cognition in children

NIH-funded research State University of New York at Buffalo · NIH-10878970

This study looks at how different chemicals in the environment might affect the thinking skills and health of kids aged 6 to 11 in Uruguay, and it hopes to find out if antioxidants can help protect them from any harm.

Quick facts

Grant typeR01 grant
Study typeNIH-funded research
Funding institutionState University of New York at Buffalo NIH-funded
Lab location1 site (Amherst, United States)
Project IDNIH-10878970 on NIH RePORTER

What this research studies

This research investigates how exposure to various environmental chemicals affects oxidative stress and cognitive functions in children aged 6 to 11 years. By following a cohort of 1st-grade children in Uruguay, the study aims to understand the combined effects of these chemicals and the role of antioxidants in mitigating potential harm. Researchers will analyze data collected over several years to assess changes in cognitive abilities and oxidative stress levels. The findings could provide insights into how environmental factors influence children's health and development.

Who could benefit from this research

Good fit: Ideal candidates for this research are children aged 6 to 11 years who have been exposed to environmental chemicals.

Not a fit: Children who are not exposed to environmental chemicals or who are outside the age range of 6 to 11 years may not benefit from this research.

Why it matters

Potential benefit: If successful, this research could lead to improved understanding and strategies to protect children's cognitive health from environmental toxins.

How similar studies have performed: Previous studies have indicated potential links between chemical exposure and cognitive impairment, but this research aims to provide more comprehensive data on the effects of chemical mixtures, making it a novel approach.

Where this research is happening

Amherst, United States

Researchers

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page below.
Last reviewed 2026-06-10 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.