Impact of brain fluid volume on neurological outcomes in preterm infants with bleeding
Effects of ventricular volume and cerebral connectivity on neurological outcomes in preterm intraventricular hemorrhage
This study looks at how the amount of fluid in the brains of very preterm babies with brain bleeding affects their development and thinking skills, with the hope of finding ways to help them grow and learn better.
Quick facts
| Grant type | R01 grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Washington University NIH-funded |
| Lab location | 1 site (Saint Louis, United States) |
| Project ID | NIH-11004959 on NIH RePORTER |
What this research studies
This research investigates how the volume of fluid in the brain affects neurological outcomes in very preterm infants who experience bleeding in the brain. By using advanced imaging techniques, the study aims to understand the relationship between brain structure and function, particularly focusing on how changes in brain fluid volume can influence connectivity in the brain. The goal is to identify critical factors that contribute to cognitive deficits and disabilities in these vulnerable infants, ultimately improving treatment strategies.
Who could benefit from this research
Good fit: Ideal candidates for this research are very preterm infants born at or before 32 weeks of gestation who have experienced intraventricular hemorrhage.
Not a fit: Patients who are not preterm or who do not have a history of brain bleeding may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to better management and treatment options for preterm infants suffering from brain injuries, potentially reducing long-term neurological disabilities.
How similar studies have performed: Previous research has shown promising results in understanding the neurological impacts of brain fluid volume in similar populations, indicating that this approach has potential for significant insights.
Where this research is happening
Saint Louis, United States
- Washington University — Saint Louis, United States (Active)
Researchers
- Principal investigator: Smyser, Christopher Daniel — Washington University
- Study coordinator: Smyser, Christopher Daniel
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.