Impact of air pollution and early life stress on children's learning difficulties

Effects of Prenatal Exposure to Air Pollution and Early Life Stress on Dopaminergic and Cognitive Systems and Their Contributions to Environmentally-Associated Learning Difficulties

NIH-funded research New York State Psychiatric Institute Dba Research Foundation for Mental Hygiene, INC · NIH-10909869

This study looks at how being exposed to air pollution and stress before birth can impact how well children from low-income communities learn and think, using animal models to understand the effects on their brains.

Quick facts

Grant typeNIH-funded research
Study typeNIH-funded research
Funding institutionNew York State Psychiatric Institute Dba Research Foundation for Mental Hygiene, INC NIH-funded
Lab location1 site (New York, United States)
Project IDNIH-10909869 on NIH RePORTER

What this research studies

This research investigates how prenatal exposure to air pollution and early life stress affects children's cognitive development and learning abilities. It focuses on children from economically disadvantaged communities who are more likely to face these environmental challenges. By studying biological and cognitive pathways, the research aims to understand how these factors contribute to learning difficulties. The study utilizes animal models to explore the effects of these exposures on brain systems related to dopamine, which is crucial for cognitive functions like attention and learning.

Who could benefit from this research

Good fit: Ideal candidates for this research are children aged 0-11 years who have been exposed to prenatal air pollution and early life stress, particularly those from economically disadvantaged backgrounds.

Not a fit: Patients who are not affected by prenatal air pollution or early life stress, or those outside the age range of 0-11 years, may not benefit from this research.

Why it matters

Potential benefit: If successful, this research could lead to improved understanding and interventions for learning difficulties in children exposed to adverse environmental conditions.

How similar studies have performed: Previous research has shown that environmental factors like air pollution can significantly impact cognitive development, suggesting that this study builds on established findings.

Where this research is happening

New York, United States

Researchers

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page below.
Last reviewed 2026-06-13 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.