IMPAACT: improving HIV care for pregnant people, babies, children, and teens
IMPAACT Leadership Group
This program runs clinical studies to find safer, longer-lasting HIV and TB treatments and ways some people might safely pause HIV medicines for pregnant people, infants, children, and adolescents.
Quick facts
| Grant type | NIH-funded research |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Johns Hopkins University NIH-funded |
| Lab location | 1 site (Baltimore, United States) |
| Project ID | NIH-11457795 on NIH RePORTER |
What this research studies
From a patient perspective, IMPAACT coordinates clinics and hospitals worldwide to enroll pregnant and postpartum people, infants, children, and teens with or at risk for HIV. It tests drug dosing, safety, how medicines behave in bodies, longer-acting formulations, and TB prevention and treatment options. Some projects try new approaches aimed at reducing or clearing HIV reservoirs so a person might maintain control without daily antiretroviral therapy. Participation typically involves clinic visits, blood samples or other specimens, and follow-up monitoring.
Who could benefit from this research
Good fit: Ideal candidates include pregnant or postpartum people with HIV and infants, children, or adolescents living with or exposed to HIV or TB who meet the specific trial’s age and health criteria.
Not a fit: People who are not within the targeted age or pregnancy groups, those without HIV/TB exposure, or individuals with medical conditions that exclude them from a given trial likely would not benefit directly.
Why it matters
Potential benefit: If successful, this work could lead to safer, more effective HIV and TB treatments for pregnant people, infants, children, and adolescents and may identify ways for some people to stop daily HIV drugs under medical supervision.
How similar studies have performed: Previous IMPAACT and other pediatric and maternal HIV trials have led to improved drug dosing, safety information, and prevention strategies, and this work builds on that track record while testing new long-acting drugs and remission approaches.
Where this research is happening
Baltimore, United States
- Johns Hopkins University — Baltimore, United States (Active)
Researchers
- Principal investigator: Nachman, Sharon a — Johns Hopkins University
- Study coordinator: Nachman, Sharon a
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.