IMPAACT: Improving HIV and TB care for pregnant people, babies, children, and teens
IMPAACT Leadership Group
This network tests safer, longer-lasting HIV and TB treatments and looks for ways some people might control HIV without daily drugs, focused on pregnant and postpartum people, infants, children, and adolescents worldwide.
Quick facts
| Grant type | NIH-funded research |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Johns Hopkins University NIH-funded |
| Lab location | 1 site (Baltimore, United States) |
| Project ID | NIH-11457788 on NIH RePORTER |
What this research studies
As a patient or parent, I would join trials run by a global network that aims to find HIV and TB medicines that are safe and practical for pregnant people, newborns, children, and teens. The program studies dosing and safety across ages, compares longer-acting drugs, and explores strategies to achieve ART-free remission in some young people. It also addresses TB prevention, diagnosis, and treatment alongside HIV and examines complications and co-infections. Sites work with hospitals and communities in multiple countries to enroll participants and collect clinical and laboratory data.
Who could benefit from this research
Good fit: Ideal candidates are pregnant or postpartum people with HIV, infants, children, and adolescents living with or at risk for HIV or TB who can attend participating clinical sites.
Not a fit: People without HIV or TB, those outside the targeted age or risk groups, or those unable to access an IMPAACT site are unlikely to receive direct benefit from participation.
Why it matters
Potential benefit: If successful, the work could bring safer, easier-to-use HIV and TB treatments, better dosing for children and pregnant people, and steps toward controlling HIV without daily medication for some individuals.
How similar studies have performed: Previous IMPAACT and related pediatric and maternal HIV trials have improved dosing and access to safer antiretrovirals, though approaches to ART-free remission remain largely experimental.
Where this research is happening
Baltimore, United States
- Johns Hopkins University — Baltimore, United States (Active)
Researchers
- Principal investigator: Nachman, Sharon a — Johns Hopkins University
- Study coordinator: Nachman, Sharon a
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.