IMPAACT: global leadership for maternal, pediatric, and adolescent HIV care
IMPAACT Leadership Group
['FUNDING_OTHER'] · JOHNS HOPKINS UNIVERSITY · NIH-11238425
This network runs clinical trials of safer, longer-lasting HIV and TB treatments and strategies to allow treatment-free remission for pregnant people, infants, children, and adolescents affected by HIV.
Quick facts
| Phase | ['FUNDING_OTHER'] |
|---|---|
| Study type | Nih_funding |
| Sex | All |
| Sponsor | JOHNS HOPKINS UNIVERSITY (nih funded) |
| Locations | 1 site (BALTIMORE, UNITED STATES) |
| Trial ID | NIH-11238425 on ClinicalTrials.gov |
What this research studies
If you join IMPAACT, you'll be connected with clinical trials that test drug dosing, safety, and how well new treatments work over time for pregnant and postpartum people, babies, children, and teens with or at risk for HIV. Trials include drug pharmacokinetics, safety monitoring, studies aimed at long-acting medicines, and approaches to reduce or stop daily antiretroviral therapy. The network also studies TB prevention, diagnosis, and treatment in populations with and without HIV. Results help guide approvals and treatment guidelines used in clinics worldwide.
Who could benefit from this research
Good fit: Ideal participants are pregnant or postpartum people, infants, children, and adolescents living with or at risk for HIV, and sometimes those with or at risk for TB, who can attend participating clinic sites.
Not a fit: People without HIV or TB, or those outside the network's age or clinical eligibility criteria, are unlikely to benefit directly from these trials.
Why it matters
Potential benefit: Successful work could bring safer, simpler, and longer-lasting HIV and TB treatments and new ways to reduce or stop daily antiretroviral therapy for young people and pregnant/postpartum people.
How similar studies have performed: Previous IMPAACT and other clinical trials have improved ART safety and dosing for children and pregnant people, though ART-free remission approaches remain experimental.
Where this research is happening
BALTIMORE, UNITED STATES
- JOHNS HOPKINS UNIVERSITY — BALTIMORE, UNITED STATES (ACTIVE)
Researchers
- Principal investigator: NACHMAN, SHARON A — JOHNS HOPKINS UNIVERSITY
- Study coordinator: NACHMAN, SHARON A
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.
Conditions: Acquired Immune Deficiency Syndrome Virus, Acquired Immunodeficiency Syndrome Virus