Immunotherapy for colorectal cancer in Nigeria
Addressing cancer disparities in Nigeria through Immuno-oncology Research – The NOLA Program
This program aims to bring immunotherapy to people in Nigeria whose colorectal cancers show MSI-high features and may respond well.
Quick facts
| Grant type | NIH-funded research |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Sloan-Kettering Inst Can Research NIH-funded |
| Lab location | 1 site (New York, United States) |
| Project ID | NIH-11393459 on NIH RePORTER |
What this research studies
You would have your tumor tested for microsatellite instability (MSI) and give blood and tissue samples so researchers can study immune markers. People with MSI-high tumors may be offered participation in a new immunotherapy trial being launched in the region, while others help by contributing samples for biomarker research. The team will compare results with U.S. patient data to understand differences in tumor immune biology in African and African-descended populations. The program also supports local lab capacity and training so testing and care can continue after the project ends.
Who could benefit from this research
Good fit: Ideal candidates are people in Nigeria diagnosed with colorectal cancer whose tumors test MSI-high and who can attend participating clinics.
Not a fit: People whose tumors are MSI-stable or who cannot travel to participating sites are unlikely to directly benefit from the immunotherapy trial.
Why it matters
Potential benefit: If successful, this work could expand access to effective immunotherapy for Nigerian and other African-descended patients with MSI-high colorectal cancer.
How similar studies have performed: Immunotherapy has worked well for MSI-high colorectal cancer in high-income countries, but it has not been widely tested in African populations.
Where this research is happening
New York, United States
- Sloan-Kettering Inst Can Research — New York, United States (Active)
Researchers
- Principal investigator: Kingham, T Peter — Sloan-Kettering Inst Can Research
- Study coordinator: Kingham, T Peter
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.