Immunogen Core: High-Quality Immunogens and Reagents for PlanB Projects
Official title: Immunogen Core
Funded at Scripps Research Institute, the · NIH-11404853 · Data updated 2026-11-12
A core team will carefully choose and produce high-quality immunogens and reagents to support PlanB projects and help elicit durable antibody responses and memory B cells.
Quick facts
| Grant type | P01 program project |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Scripps Research Institute, the NIH-funded |
| Lab location | 1 site (La Jolla, United States) |
| Project start | September 5, 2025 |
| Project end | June 30, 2030 |
| Funding year | 2026 |
| Award (this year) | $253,742 |
| NIH project number | 5P01HL183482-02 |
| Project ID | NIH-11404853 on NIH RePORTER |
Who could benefit from this research
✓Could help
Ideal candidates are individuals affected by conditions related to B cell–mediated immunity who may participate in future translational studies or trials using PlanB-derived immunogens.
✕Less likely to help
This core does not involve direct patient recruitment or clinical procedures; benefits are realized through improved tools for subsequent patient-facing research.
What this research studies
This grant funds a core service that selects and manufactures immunogens and immunological reagents for PlanB Projects 1–4. The goal is to generate strong, lasting serum neutralization and robust memory B cell responses in the context of the PlanB consortium. Researchers will rely on this core for expert material preparation, quality control, and supply of reagents tailored to the project needs. The work is designed to strengthen the translational potential of PlanB by enabling reliable, reproducible immunogens across multiple studies.
Why it matters
Potential benefit: If successful, patients may benefit from more effective immune responses and durable protection in related vaccine or therapeutic efforts.
How similar studies have gone: Similar immunogen production cores have supported robust immune responses in vaccine research, with prior successes in producing quality reagents for multiple projects.
Where this research is happening
-
Scripps Research Institute, the
La Jolla, United States Active
Researchers
- Principal investigator: Cottrell, Christopher Andrew — Scripps Research Institute, the
- Study coordinator: Cottrell, Christopher Andrew
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About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page.