Immune testing hub for COVID‑19, flu, and dengue vaccines
Immune Phenotyping Core
['FUNDING_OTHER'] · ICAHN SCHOOL OF MEDICINE AT MOUNT SINAI · NIH-11481641
This program offers lab tests that track immune responses in people after COVID‑19, influenza, or dengue vaccination or infection.
Quick facts
| Phase | ['FUNDING_OTHER'] |
|---|---|
| Study type | Nih_funding |
| Sex | All |
| Sponsor | ICAHN SCHOOL OF MEDICINE AT MOUNT SINAI (nih funded) |
| Locations | 1 site (NEW YORK, UNITED STATES) |
| Trial ID | NIH-11481641 on ClinicalTrials.gov |
What this research studies
From your perspective, the team will use blood and other tissue samples from people who were vaccinated or infected to look at antibody levels and immune signaling proteins. They will run established antibody tests, measure cytokines and chemokines in plasma, and profile immune cells with advanced spectral flow cytometry. The Core supplies assays, reagents, and protocols to support multiple projects studying SARS‑CoV‑2, influenza, and dengue. Their work includes testing secreted antibodies from cultured human tonsil tissues treated with different vaccines.
Who could benefit from this research
Good fit: Ideal participants are people who have had COVID‑19, influenza, or dengue infection or who have received related vaccines and can provide blood or eligible tissue samples.
Not a fit: People without exposure or vaccination to these viruses, or those seeking direct clinical treatment rather than contributing samples, are unlikely to receive personal medical benefit from this Core.
Why it matters
Potential benefit: If successful, the work could improve how we detect and understand immune responses to these vaccines and infections, helping guide better vaccines and diagnostics.
How similar studies have performed: Serology, cytokine profiling, and spectral flow cytometry are established methods that have already provided useful insights into vaccine and infection responses, though combining them across multiple viruses is a broader approach.
Where this research is happening
NEW YORK, UNITED STATES
- ICAHN SCHOOL OF MEDICINE AT MOUNT SINAI — NEW YORK, UNITED STATES (ACTIVE)
Researchers
- Principal investigator: FERNANDEZ-SESMA, ANA — ICAHN SCHOOL OF MEDICINE AT MOUNT SINAI
- Study coordinator: FERNANDEZ-SESMA, ANA
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.