Imagnostix — a blood test to detect Alzheimer's early
Development of "Imagnostix": A Liquid Biopsy System for Alzheimer's Disease
['FUNDING_OTHER'] · 5M BIOMED, LLC · NIH-11186422
Imagnostix is a new blood test that looks for Alzheimer's-related proteins to find early brain changes in people with memory concerns or at risk for Alzheimer's.
Quick facts
| Phase | ['FUNDING_OTHER'] |
|---|---|
| Study type | Nih_funding |
| Sex | All |
| Sponsor | 5M BIOMED, LLC (nih funded) |
| Locations | 1 site (JOHNS CREEK, UNITED STATES) |
| Trial ID | NIH-11186422 on ClinicalTrials.gov |
What this research studies
If I join, I'll give blood samples so researchers can look for Alzheimer's-related proteins such as amyloid-beta 42 using a liquid biopsy platform called Imagnostix. They plan to compare blood results to established tests like PET scans and cerebrospinal fluid measures and may follow participants over time to see how markers change. The goal is to detect Alzheimer's changes before or at the earliest symptoms so people can be matched to treatments like the newly approved drugs or monitored more easily. The project is led by 5M BIOMED and will run at sites near Johns Creek, GA or partnering clinics.
Who could benefit from this research
Good fit: Ideal candidates are older adults with memory complaints, mild cognitive impairment, a family history of Alzheimer's, or other risk factors for dementia.
Not a fit: People with established advanced dementia, no Alzheimer's-related pathology, or conditions that prevent blood sampling may not get direct benefit from this test.
Why it matters
Potential benefit: If successful, this could make diagnosing Alzheimer's earlier and easier with a simple blood test, helping people access appropriate treatments sooner.
How similar studies have performed: Other blood-based Alzheimer's biomarker studies have shown promising results and some tests are emerging clinically, but broader validation is still needed.
Where this research is happening
JOHNS CREEK, UNITED STATES
- 5M BIOMED, LLC — JOHNS CREEK, UNITED STATES (ACTIVE)
Researchers
- Principal investigator: LI, YUANCHENG — 5M BIOMED, LLC
- Study coordinator: LI, YUANCHENG
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.