Imaging the dynamic state of brain tumors in patients

MOSAIC: Imaging Human Tissue State Dynamics In Vivo

NIH-funded research Mayo Clinic Arizona · NIH-11186083

This study is looking at ways to improve treatment for glioblastoma, a tough brain tumor, by using advanced MRI scans to better understand how the tumor behaves and interacts with its surroundings, which could help doctors provide more effective and personalized care for patients.

Quick facts

Grant typeNIH-funded research
Study typeNIH-funded research
Funding institutionMayo Clinic Arizona NIH-funded
Lab location1 site (Scottsdale, United States)
Project IDNIH-11186083 on NIH RePORTER

What this research studies

This research focuses on glioblastoma, a common and aggressive brain tumor in adults, and aims to improve treatment outcomes by using advanced imaging techniques. Instead of relying solely on traditional tissue sampling, which has limitations, the study employs multi-parametric magnetic resonance imaging (MRI) to capture various physiological biomarkers associated with tumor behavior. By understanding how tumor cells interact with their surrounding environment, the research seeks to enhance non-invasive diagnosis and monitoring of disease progression, ultimately leading to better-targeted therapies for patients.

Who could benefit from this research

Good fit: Ideal candidates for this research are adults diagnosed with glioblastoma who are seeking innovative treatment options.

Not a fit: Patients with non-brain tumors or those who are not diagnosed with glioblastoma may not benefit from this research.

Why it matters

Potential benefit: If successful, this research could lead to more effective and personalized treatment strategies for patients with glioblastoma.

How similar studies have performed: Previous research has shown promise in using advanced imaging techniques for tumor characterization, indicating potential success for this novel approach.

Where this research is happening

Scottsdale, United States

Researchers

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page below.
Last reviewed 2026-06-13 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.