Imaging the dynamic state of brain tumors in patients
Official title: MOSAIC: Imaging Human Tissue State Dynamics In Vivo
Funded at Mayo Clinic Arizona · NIH-11186083 · Data updated 2026-11-12
This study is looking at ways to improve treatment for glioblastoma, a tough brain tumor, by using advanced MRI scans to better understand how the tumor behaves and interacts with its surroundings, which could help doctors provide more effective and personalized care for patients.
Quick facts
| Grant type | NIH-funded research |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Mayo Clinic Arizona NIH-funded |
| Lab location | 1 site (Scottsdale, United States) |
| Project start | September 18, 2023 |
| Project end | August 31, 2028 |
| Funding year | 2024 |
| Award (this year) | $13,791 |
| NIH project number | 3U54CA274504-02S1 |
| Project ID | NIH-11186083 on NIH RePORTER |
Who could benefit from this research
✓Could help
Ideal candidates for this research are adults diagnosed with glioblastoma who are seeking innovative treatment options.
✕Less likely to help
Patients with non-brain tumors or those who are not diagnosed with glioblastoma may not benefit from this research.
What this research studies
This research focuses on glioblastoma, a common and aggressive brain tumor in adults, and aims to improve treatment outcomes by using advanced imaging techniques. Instead of relying solely on traditional tissue sampling, which has limitations, the study employs multi-parametric magnetic resonance imaging (MRI) to capture various physiological biomarkers associated with tumor behavior. By understanding how tumor cells interact with their surrounding environment, the research seeks to enhance non-invasive diagnosis and monitoring of disease progression, ultimately leading to better-targeted therapies for patients.
Why it matters
Potential benefit: If successful, this research could lead to more effective and personalized treatment strategies for patients with glioblastoma.
How similar studies have gone: Previous research has shown promise in using advanced imaging techniques for tumor characterization, indicating potential success for this novel approach.
Where this research is happening
-
Mayo Clinic Arizona
Scottsdale, United States Active
Researchers
- Principal investigator: Swanson, Kristin R — Mayo Clinic Arizona
- Study coordinator: Swanson, Kristin R
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page.