Imaging the changes in brain tissue for glioblastoma patients
MOSAIC: Imaging Human Tissue State Dynamics In Vivo
This study is looking at ways to better understand and treat glioblastoma, a tough brain tumor, by using advanced MRI scans to see how the tumor interacts with nearby cells, which could help improve diagnosis and treatment without needing to take tissue samples.
Quick facts
| Grant type | NIH-funded research |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Mayo Clinic Arizona NIH-funded |
| Lab location | 1 site (Scottsdale, United States) |
| Project ID | NIH-10930915 on NIH RePORTER |
What this research studies
This research focuses on glioblastoma, a severe brain tumor with a low survival rate, and aims to improve treatment strategies by using advanced imaging techniques. Instead of relying solely on traditional tissue sampling, which has limitations, the study employs multi-parametric magnetic resonance imaging (MRI) to capture various physiological markers of the tumor and its environment. This approach seeks to understand how tumor cells interact with surrounding non-tumoral cells, which could influence disease progression and treatment response. By refining the interpretation of imaging results, the research aims to enhance non-invasive diagnosis and monitoring of glioblastoma.
Who could benefit from this research
Good fit: Ideal candidates for this research are adults diagnosed with glioblastoma who are undergoing treatment.
Not a fit: Patients with other types of brain tumors or those who are not diagnosed with glioblastoma may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to more effective and personalized treatment options for glioblastoma patients.
How similar studies have performed: Previous research has shown promise in using advanced imaging techniques for tumor characterization, indicating potential success for this novel approach.
Where this research is happening
Scottsdale, United States
- Mayo Clinic Arizona — Scottsdale, United States (Active)
Researchers
- Principal investigator: Swanson, Kristin R — Mayo Clinic Arizona
- Study coordinator: Swanson, Kristin R
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.