Imaging techniques for understanding mitral valve prolapse

PET/MRI imaging of mitral valve prolapse

['FUNDING_R01'] · ICAHN SCHOOL OF MEDICINE AT MOUNT SINAI · NIH-10914239

This study is looking at how inflammation and scarring in the heart affect people with mitral valve prolapse (MVP) and aims to find better ways to understand and manage the risks for those living with this condition.

Quick facts

Phase['FUNDING_R01']
Study typeNih_funding
SexAll
SponsorICAHN SCHOOL OF MEDICINE AT MOUNT SINAI (nih funded)
Locations1 site (NEW YORK, UNITED STATES)
Trial IDNIH-10914239 on ClinicalTrials.gov

What this research studies

This research investigates mitral valve prolapse (MVP), a common heart condition that can lead to serious complications like heart failure and sudden cardiac death. The study uses advanced imaging techniques, specifically PET/MRI, to explore the relationship between inflammation, scarring, and arrhythmias in patients with MVP. By analyzing how glucose uptake in the heart correlates with the severity of MVP and related symptoms, the research aims to improve risk assessment and management strategies for affected patients.

Who could benefit from this research

Good fit: Ideal candidates for this research are individuals diagnosed with mitral valve prolapse, particularly those experiencing symptoms or complications.

Not a fit: Patients without mitral valve prolapse or those with unrelated cardiac conditions may not benefit from this research.

Why it matters

Potential benefit: If successful, this research could lead to better diagnostic tools and treatment options for patients with mitral valve prolapse.

How similar studies have performed: Previous studies have shown promising results using imaging techniques to assess cardiac conditions, suggesting that this approach may yield valuable insights into mitral valve prolapse.

Where this research is happening

NEW YORK, UNITED STATES

Researchers

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page below.

View on NIH RePORTER →

Conditions: Barlows Syndrome

Last reviewed 2026-05-15 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.