Imaging techniques for understanding mitral valve prolapse
Official title: PET/MRI imaging of mitral valve prolapse
Funded at Icahn School of Medicine at Mount Sinai · NIH-10914239 · Data updated 2026-11-12
This study is looking at how inflammation and scarring in the heart affect people with mitral valve prolapse (MVP) and aims to find better ways to understand and manage the risks for those living with this condition.
Quick facts
| Grant type | R01 grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Icahn School of Medicine at Mount Sinai NIH-funded |
| Lab location | 1 site (New York, United States) |
| Project start | August 25, 2023 |
| Project end | June 30, 2028 |
| Funding year | 2024 |
| Award (this year) | $2,047,367 |
| NIH project number | 5R01HL166720-02 |
| Project ID | NIH-10914239 on NIH RePORTER |
Who could benefit from this research
✓Could help
Ideal candidates for this research are individuals diagnosed with mitral valve prolapse, particularly those experiencing symptoms or complications.
✕Less likely to help
Patients without mitral valve prolapse or those with unrelated cardiac conditions may not benefit from this research.
What this research studies
This research investigates mitral valve prolapse (MVP), a common heart condition that can lead to serious complications like heart failure and sudden cardiac death. The study uses advanced imaging techniques, specifically PET/MRI, to explore the relationship between inflammation, scarring, and arrhythmias in patients with MVP. By analyzing how glucose uptake in the heart correlates with the severity of MVP and related symptoms, the research aims to improve risk assessment and management strategies for affected patients.
Why it matters
Potential benefit: If successful, this research could lead to better diagnostic tools and treatment options for patients with mitral valve prolapse.
How similar studies have gone: Previous studies have shown promising results using imaging techniques to assess cardiac conditions, suggesting that this approach may yield valuable insights into mitral valve prolapse.
Where this research is happening
-
Icahn School of Medicine at Mount Sinai
New York, United States Active
Researchers
- Principal investigator: Trivieri, Maria Giovanna — Icahn School of Medicine at Mount Sinai
- Study coordinator: Trivieri, Maria Giovanna
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About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page.