Imaging techniques for understanding blood flow issues in diabetic patients
Official title: Multi-isotope Hybrid PET/CT Imaging of Peripheral Artery Disease in Diabetes
Funded at Yale University · NIH-11237395 · Data updated 2026-11-12
This study is looking at how diabetes impacts blood flow and nerve health in people with peripheral artery disease (PAD) by using special imaging to see what's happening in their legs, with the goal of finding better ways to manage and treat their condition.
Quick facts
| Grant type | R01 grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Yale University NIH-funded |
| Lab location | 1 site (New Haven, United States) |
| Project start | December 19, 2022 |
| Project end | November 30, 2025 |
| Funding year | 2025 |
| Award (this year) | $150,048 |
| NIH project number | 3R01HL163640-03S1 |
| Project ID | NIH-11237395 on NIH RePORTER |
Who could benefit from this research
✓Could help
Ideal candidates for this research are individuals with diabetes who are experiencing symptoms of peripheral artery disease, such as leg pain or critical limb ischemia.
✕Less likely to help
Patients without diabetes or those who do not have symptoms of peripheral artery disease may not benefit from this research.
What this research studies
This research investigates how diabetes affects blood flow and nerve function in patients with peripheral artery disease (PAD). It uses advanced imaging techniques, specifically multi-isotope hybrid PET/CT imaging, to visualize blood flow and sympathetic nerve activity in the legs of diabetic patients. By understanding these mechanisms, the research aims to identify the severity of PAD and its complications, which can lead to better management and treatment options for affected individuals.
Why it matters
Potential benefit: If successful, this research could lead to improved diagnostic methods and treatment strategies for patients with diabetes and peripheral artery disease.
How similar studies have gone: Previous research has shown that advanced imaging techniques can effectively enhance our understanding of vascular and nerve function in diabetic patients, indicating a promising approach in this area.
Where this research is happening
-
Yale University
New Haven, United States Active
Researchers
- Principal investigator: Sinusas, Albert J — Yale University
- Study coordinator: Sinusas, Albert J
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Imaging techniques for understanding blood flow issues in diabetic patients
This study is looking at how diabetes impacts blood flow and nerve function in people with peripheral artery disease (PAD), especially those who have leg pain or serious circulation issues, to help understand how these problems affect their everyday lives.
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About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page.