Imaging techniques for understanding blood flow issues in diabetic patients
Multi-isotope Hybrid PET/CT Imaging of Peripheral Artery Disease in Diabetes
This study is looking at how diabetes impacts blood flow and nerve function in people with peripheral artery disease (PAD), especially those who have leg pain or serious circulation issues, to help understand how these problems affect their everyday lives.
Quick facts
| Grant type | R01 grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Yale University NIH-funded |
| Lab location | 1 site (New Haven, United States) |
| Project ID | NIH-11001194 on NIH RePORTER |
What this research studies
This research investigates how diabetes affects blood flow and nerve function in patients with peripheral artery disease (PAD). It uses advanced imaging techniques, specifically multi-isotope hybrid PET/CT, to visualize and quantify blood flow and sympathetic nerve activity in the legs. By understanding these mechanisms, the research aims to identify the severity of PAD and its impact on patients' daily lives. The study focuses on patients experiencing symptoms like leg pain or critical limb ischemia due to vascular insufficiency.
Who could benefit from this research
Good fit: Ideal candidates for this research are individuals with diabetes who are experiencing symptoms of peripheral artery disease, such as leg pain or critical limb ischemia.
Not a fit: Patients without diabetes or those who do not have symptoms of peripheral artery disease may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to improved diagnostic methods and treatment strategies for patients with diabetes and peripheral artery disease.
How similar studies have performed: Previous research has shown promising results using advanced imaging techniques to assess vascular conditions, indicating potential success for this novel approach.
Where this research is happening
New Haven, United States
- Yale University — New Haven, United States (Active)
Researchers
- Principal investigator: Sinusas, Albert J — Yale University
- Study coordinator: Sinusas, Albert J
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.