Imaging single proteins to understand their properties and interactions
Optical imaging of size, charge, mobility and binding of single proteins
This study is working on a new way to quickly and easily analyze proteins in the body without using any labels, which could help doctors better understand diseases and improve treatment options for patients.
Quick facts
| Grant type | R01 grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Arizona State University-Tempe Campus NIH-funded |
| Lab location | 1 site (Tempe, United States) |
| Project ID | NIH-10903989 on NIH RePORTER |
What this research studies
This research focuses on developing a new detection platform that can analyze single proteins by measuring their size, charge, and mobility without the need for labels. By combining existing technologies like gel and capillary electrophoresis, this innovative approach aims to simplify the process of protein analysis, making it faster and more efficient. Patients may benefit from improved diagnostic capabilities based on molecular biomarkers, which can lead to better disease understanding and treatment options.
Who could benefit from this research
Good fit: Ideal candidates for this research are individuals with conditions that can be diagnosed or treated based on protein biomarkers.
Not a fit: Patients with diseases not related to protein biomarkers or those who do not require protein analysis for diagnosis may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could enhance the accuracy of disease diagnosis and treatment by providing detailed insights into protein interactions.
How similar studies have performed: Other research has shown success in developing advanced protein analysis techniques, but this specific approach is innovative and aims to fill existing gaps in single molecule detection.
Where this research is happening
Tempe, United States
- Arizona State University-Tempe Campus — Tempe, United States (Active)
Researchers
- Principal investigator: Wang, Shaopeng — Arizona State University-Tempe Campus
- Study coordinator: Wang, Shaopeng
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.