Imaging how the liver processes energy in fatty liver diseases
Imaging Hepatic Energy Metabolism in NAFLD/NASH
This study is looking at new imaging methods to see how the liver processes energy in people with nonalcoholic fatty liver disease (NAFLD) and nonalcoholic steatohepatitis (NASH), which could help us understand the disease better and find new ways to treat it.
Quick facts
| Grant type | R01 grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | University of Florida NIH-funded |
| Lab location | 1 site (Gainesville, United States) |
| Project ID | NIH-11010021 on NIH RePORTER |
What this research studies
This research focuses on developing advanced imaging techniques to better understand how the liver metabolizes energy in conditions like nonalcoholic fatty liver disease (NAFLD) and nonalcoholic steatohepatitis (NASH). By using specialized magnetic resonance imaging with labeled substrates, the study aims to assess changes in carbohydrate and fatty acid metabolism in mouse models of these diseases. The findings could provide insights into the progression of liver disease and help identify potential therapeutic targets.
Who could benefit from this research
Good fit: Ideal candidates for this research are individuals diagnosed with nonalcoholic fatty liver disease or nonalcoholic steatohepatitis.
Not a fit: Patients with alcoholic liver disease or other unrelated liver conditions may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to improved diagnostic methods and treatments for patients with fatty liver diseases.
How similar studies have performed: Previous research has shown promise in using metabolic imaging techniques for studying liver diseases, indicating a potential for success in this novel approach.
Where this research is happening
Gainesville, United States
- University of Florida — Gainesville, United States (Active)
Researchers
- Principal investigator: Merritt, Matthew E — University of Florida
- Study coordinator: Merritt, Matthew E
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.