NIH-funded research NIH-funded research

Imaging and Radiation Quality Assurance for Cancer Trials

Official title: Imaging and Radiation Oncology Core (IROC) Group

Funded at American College of Radiology · NIH-11291354 · Data updated 2026-11-12

A national quality assurance program helps ensure imaging and radiation therapy in cancer trials are accurate and consistent so patients receive safe, effective care.

Quick facts

Grant typeNIH-funded research
Study typeNIH-funded research
Funding institutionAmerican College of Radiology
NIH-funded
Lab location1 site (Reston, United States)
Project startMay 26, 2014
Project endFebruary 29, 2032
Funding year2026
Award (this year)$8,727,840
NIH project number2U24CA180803-12
Project IDNIH-11291354 on NIH RePORTER

Who could benefit from this research

Could help

Patients enrolled in NCI-supported cancer clinical trials that involve imaging and radiotherapy.

Less likely to help

Patients not participating in or not undergoing imaging/RT in a trial may not directly benefit.

What this research studies

This grant supports the Imaging and Radiation Oncology Core (IROC) to provide scientific and technical expertise for QA and image data management in cancer clinical trials. It coordinates across multiple regional centers to standardize imaging and radiotherapy procedures, streamline workflows, and reduce the burden on submitting sites. The goal is to make trial data trustworthy and comparable so that treatment decisions for patients are based on high-quality information. The effort involves site qualification, trial design support, credentialing, and ongoing QA activities across the NCTN/CTEP network.

Why it matters

Potential benefit: If successful, patients in cancer trials could receive more reliable imaging and radiation therapy assessments, improving the safety and effectiveness of treatments.

How similar studies have gone: Previous QA programs have improved consistency and data integrity across multicenter trials, reinforcing the value of standardized imaging and RT QA.

Where this research is happening

  • American College of Radiology
    Reston, United States
    Active

Researchers

  • Principal investigator: Knopp, Michael V — American College of Radiology
  • Study coordinator: Knopp, Michael V

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page.
Last reviewed 2026-11-14 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.