IGNITE-TX helps families access genetic testing for hereditary cancers
Official title: IGNITE-TX
Funded at University of Tx Md Anderson Can Ctr · NIH-11447168 · Data updated 2026-11-12
A project to make genetic testing for hereditary breast/ovarian cancer and Lynch syndrome easier to access for people with limited resources.
Quick facts
| Grant type | R01 grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | University of Tx Md Anderson Can Ctr NIH-funded |
| Lab location | 1 site (Houston, United States) |
| Project start | July 1, 2026 |
| Project end | June 30, 2031 |
| Funding year | 2026 |
| Award (this year) | $706,777 |
| NIH project number | 1R01CA308143-01A1 |
| Project ID | NIH-11447168 on NIH RePORTER |
Who could benefit from this research
✓Could help
Ideal candidates include individuals with or at risk for HBOC or Lynch syndrome who face barriers to accessing genetic services, especially in low-resource or safety-net settings.
✕Less likely to help
Some individuals may not experience immediate benefit if they are not at elevated risk or if they choose not to pursue testing.
What this research studies
This program tests a proactive way to connect families to genetic testing and counseling when resources are scarce. It uses family genetic navigators and digital tools to reach more at-risk relatives beyond the first affected patient. The study will measure uptake of genetic testing at six months, along with knowledge, confidence, and family communication, and will examine how to best implement the approach in low-resource settings. Findings will guide scalable, sustainable strategies to reduce barriers and improve early identification of at-risk individuals.
Why it matters
Potential benefit: If successful, more high-risk individuals will learn their genetic status sooner, enabling earlier prevention or targeted care.
How similar studies have gone: Prior programs have shown that navigation and targeted outreach can improve uptake of genetic testing in underserved groups, but scalability and long-term impact remain to be proven.
Where this research is happening
-
University of Tx Md Anderson Can Ctr
Houston, United States Active
Researchers
- Principal investigator: Rauh-Hain, Jose Alejandro — University of Tx Md Anderson Can Ctr
- Study coordinator: Rauh-Hain, Jose Alejandro
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page.