Identifying urine metabolites that predict weight gain during pregnancy in South African women with HIV
Official title: Metabolomic predictors of weight gain during pregnancy and the postpartum period in South African women living with HIV
Funded at University of Cape Town · NIH-11000408 · Data updated 2026-11-12
This study is looking at how certain substances in urine can help predict if women with HIV might gain too much weight during and after pregnancy, so we can find ways to support their health and prevent future issues like diabetes and heart problems.
Quick facts
| Grant type | NIH-funded research |
|---|---|
| Study type | NIH-funded research |
| Funding institution | University of Cape Town NIH-funded |
| Lab location | 1 site (Rondebosch, South Africa) |
| Project start | September 1, 2024 |
| Project end | August 31, 2029 |
| Funding year | 2024 |
| Award (this year) | $113,048 |
| NIH project number | 1K43TW012887-01 |
| Project ID | NIH-11000408 on NIH RePORTER |
Who could benefit from this research
✓Could help
Ideal candidates for this research are pregnant women living with HIV in South Africa who are at risk of excessive weight gain.
✕Less likely to help
Patients who are not pregnant or do not have HIV may not receive any benefit from this research.
What this research studies
This research focuses on understanding how certain metabolites in urine can predict excessive weight gain during pregnancy and postpartum weight retention in women living with HIV. By identifying these biomarkers, the study aims to enable early interventions for those at risk of developing metabolic conditions such as diabetes and cardiovascular diseases. The research will involve collecting and analyzing urine samples from participants to find patterns that indicate potential weight issues. This approach is particularly important for improving health outcomes in this vulnerable population.
Why it matters
Potential benefit: If successful, this research could lead to targeted interventions that help manage weight gain during and after pregnancy, ultimately reducing the risk of serious health complications for women living with HIV.
How similar studies have gone: Previous research has shown that identifying metabolic markers can successfully predict health outcomes in various populations, suggesting that this approach may yield valuable insights.
Where this research is happening
-
University of Cape Town
Rondebosch, South Africa Active
Researchers
- Principal investigator: Madlala , Hlengiwe — University of Cape Town
- Study coordinator: Madlala , Hlengiwe
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About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page.