Identifying tear protein markers related to pain after eye surgery
Tear protein biomarkers of refractive surgery pain
['FUNDING_OTHER'] · OREGON HEALTH & SCIENCE UNIVERSITY · NIH-11045022
This study is looking at the proteins in your tears to see if they can help predict which people might experience ongoing eye pain after surgeries like PRK and LASIK, with the hope of finding better ways to help those who are affected.
Quick facts
| Phase | ['FUNDING_OTHER'] |
|---|---|
| Study type | Nih_funding |
| Sex | All |
| Sponsor | OREGON HEALTH & SCIENCE UNIVERSITY (nih funded) |
| Locations | 1 site (PORTLAND, UNITED STATES) |
| Trial ID | NIH-11045022 on ClinicalTrials.gov |
What this research studies
This research investigates the role of tear proteins in the development of persistent ocular pain following refractive surgeries like PRK and LASIK. By analyzing tear fluid before and after these procedures, the study aims to identify biomarkers that can predict which patients are at risk for chronic pain. The approach involves advanced proteomic analysis to validate these biomarkers, potentially leading to improved treatment strategies for affected individuals. Ultimately, the goal is to enhance patient outcomes and quality of life by addressing this significant post-surgical complication.
Who could benefit from this research
Good fit: Ideal candidates for this research are individuals undergoing PRK or LASIK surgery who may be at risk for developing persistent ocular pain.
Not a fit: Patients who are not undergoing refractive surgery or those who do not experience ocular pain post-surgery may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to better prevention and treatment options for patients experiencing chronic pain after eye surgery.
How similar studies have performed: Previous research has shown promise in identifying biomarkers for pain in other contexts, suggesting potential success for this novel approach.
Where this research is happening
PORTLAND, UNITED STATES
- OREGON HEALTH & SCIENCE UNIVERSITY — PORTLAND, UNITED STATES (ACTIVE)
Researchers
- Principal investigator: AICHER, SUE A — OREGON HEALTH & SCIENCE UNIVERSITY
- Study coordinator: AICHER, SUE A
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.