NIH-funded research R01 grant

Identifying survival predictors for breast cancer patients with and without HIV in South Africa

Official title: Novel predictors of survival among breast cancer patients with/without HIV in South Africa

Funded at Wits Health Consortium (Pty), LTD · NIH-10851806 · Data updated 2026-11-12

This study is looking at how having HIV and taking HIV medicine might impact breast cancer treatment and recovery for women in South Africa, with the goal of finding better ways to help them survive and thrive.

More Breast Cancer research and trials

Quick facts

Grant typeR01 grant
Study typeNIH-funded research
Funding institutionWits Health Consortium (Pty), LTD
NIH-funded
Lab location1 site (Parktown, South Africa)
Project startJune 1, 2020
Project endMay 31, 2026
Funding year2024
Award (this year)$345,761
NIH project number5R01CA250012-05
Project IDNIH-10851806 on NIH RePORTER

Who could benefit from this research

Could help

Ideal candidates for this research include women diagnosed with breast cancer in South Africa, particularly those who are HIV positive.

Less likely to help

Patients who do not have breast cancer or are not located in South Africa may not benefit from this research.

What this research studies

This research investigates how HIV infection and antiretroviral therapy (ART) affect breast cancer treatment and outcomes among women in South Africa. By analyzing data from over 3,000 breast cancer patients, including those who are HIV positive, the study aims to identify factors that influence survival rates. The research builds on previous findings and seeks to improve understanding of the interplay between HIV and breast cancer, ultimately guiding better treatment strategies. Patients will be monitored for their clinical characteristics and treatment responses over time.

Why it matters

Potential benefit: If successful, this research could lead to improved survival rates and treatment protocols for breast cancer patients living with HIV.

How similar studies have gone: Previous studies have shown promising results in understanding the relationship between HIV and breast cancer, indicating that this research builds on established findings.

Where this research is happening

  • Wits Health Consortium (Pty), LTD
    Parktown, South Africa
    Active

Researchers

  • Principal investigator: Joffe, Maureen — Wits Health Consortium (Pty), LTD
  • Study coordinator: Joffe, Maureen

Related research

Other NIH-funded projects on the same topics.

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page.
Last reviewed 2026-11-14 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.