Identifying specific T cells that fight lung cancer
Unbiased electrothermal flow-enhanced identification of antigen-specific T cells in lung cancer
['FUNDING_R21'] · UNIVERSITY OF TX MD ANDERSON CAN CTR · NIH-10723218
This study is looking to make lung cancer treatments better by finding out which specific T cells can effectively target the cancer, so that patients can receive more personalized and effective immunotherapy options.
Quick facts
| Phase | ['FUNDING_R21'] |
|---|---|
| Study type | Nih_funding |
| Sex | All |
| Sponsor | UNIVERSITY OF TX MD ANDERSON CAN CTR (nih funded) |
| Locations | 1 site (HOUSTON, UNITED STATES) |
| Trial ID | NIH-10723218 on ClinicalTrials.gov |
What this research studies
This research focuses on improving immunotherapy for lung cancer by developing a method to identify T cells that specifically target tumor antigens. Current therapies often activate a wide range of T cells without knowing their specific targets, which can lead to ineffective treatments. The researchers aim to create unbiased techniques to better understand which T cells are effective against lung cancer, potentially leading to more personalized and effective immunotherapy options for patients. By analyzing tumor antigens and the T cells that recognize them, this study seeks to enhance the precision of cancer treatments.
Who could benefit from this research
Good fit: Ideal candidates for this research are patients diagnosed with lung cancer who are seeking innovative treatment options.
Not a fit: Patients with lung cancer who are not eligible for immunotherapy or those with other unrelated health conditions may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to more effective immunotherapies that specifically target lung cancer, improving patient outcomes.
How similar studies have performed: Other research has shown promise in identifying specific T cell responses in cancer, but this approach aims to address significant gaps in current methodologies.
Where this research is happening
HOUSTON, UNITED STATES
- UNIVERSITY OF TX MD ANDERSON CAN CTR — HOUSTON, UNITED STATES (ACTIVE)
Researchers
- Principal investigator: REUBEN, ALEXANDRE — UNIVERSITY OF TX MD ANDERSON CAN CTR
- Study coordinator: REUBEN, ALEXANDRE
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.