Identifying Shared Keys to Regeneration Across Species
Official title: A multiscale and multispecies approach for identifying shared mechanisms of limb and fin regeneration
Funded at Louisiana State Univ A&m Col Baton Rouge · NIH-11259981 · Data updated 2026-11-12
Researchers are studying salamanders and certain fish to uncover the natural signals that could help mammals regrow limbs.
Quick facts
| Grant type | NIH-funded research |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Louisiana State Univ A&m Col Baton Rouge NIH-funded |
| Lab location | 1 site (Baton Rouge, United States) |
| Project start | September 4, 2026 |
| Project end | August 31, 2031 |
| Funding year | 2026 |
| Award (this year) | $375,000 |
| NIH project number | 1R35GM161400-01 |
| Project ID | NIH-11259981 on NIH RePORTER |
Who could benefit from this research
✓Could help
Not applicable here; this grant is a basic science project using animal models and comparative data.
✕Less likely to help
There is no direct patient participation in this purely preclinical study.
What this research studies
This project uses a multiscale, cross-species approach to find common cellular and genetic factors that trigger limb and fin regeneration. By comparing highly regenerative species like axolotls and certain fish with non-regenerative benchmarks, the team aims to pinpoint conserved signals and how scar-free tissue forms. The insights could lay groundwork for future therapies to help people who have limb loss.
Why it matters
Potential benefit: If successful, the work could guide new strategies to improve limb repair and regeneration in humans.
How similar studies have gone: The approach builds on existing comparative biology methods and has potential for breakthroughs, though it remains exploratory.
Where this research is happening
-
Louisiana State Univ A&m Col Baton Rouge
Baton Rouge, United States Active
Researchers
- Principal investigator: Schneider, Igor — Louisiana State Univ A&m Col Baton Rouge
- Study coordinator: Schneider, Igor
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About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page.