Identifying risk levels in children with liver tumors
Validation of Clinical Assays for Risk Stratification of Children With Pediatric Liver Neoplasms
['FUNDING_OTHER'] · BAYLOR COLLEGE OF MEDICINE · NIH-10868737
This study is looking to help kids with liver tumors by figuring out their individual risk levels, so doctors can give them the best treatment possible—some may need stronger therapies, while others can skip the harsh side effects of high-dose chemotherapy.
Quick facts
| Phase | ['FUNDING_OTHER'] |
|---|---|
| Study type | Nih_funding |
| Sex | All |
| Sponsor | BAYLOR COLLEGE OF MEDICINE (nih funded) |
| Locations | 1 site (HOUSTON, UNITED STATES) |
| Trial ID | NIH-10868737 on ClinicalTrials.gov |
What this research studies
This research focuses on improving treatment outcomes for children diagnosed with liver tumors, specifically hepatoblastoma and hepatocellular carcinoma. By analyzing molecular biomarkers, the study aims to categorize patients based on their risk levels, which will help determine the most effective treatment strategies. The approach includes developing predictive models that can identify which patients may benefit from aggressive therapies and which can avoid unnecessary high-dose chemotherapy. This personalized treatment plan is designed to enhance survival rates and reduce treatment-related morbidity.
Who could benefit from this research
Good fit: Ideal candidates for this research are children under 21 years old diagnosed with hepatoblastoma or hepatocellular carcinoma.
Not a fit: Patients with liver tumors that are not hepatoblastoma or hepatocellular carcinoma may not receive benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to more tailored and effective treatment options for children with liver tumors, improving survival rates and quality of life.
How similar studies have performed: Previous research has successfully identified prognostic biomarkers for liver tumors, indicating that this approach has potential for meaningful advancements in treatment.
Where this research is happening
HOUSTON, UNITED STATES
- BAYLOR COLLEGE OF MEDICINE — HOUSTON, UNITED STATES (ACTIVE)
Researchers
- Principal investigator: LOPEZ-TERRADA, DOLORES — BAYLOR COLLEGE OF MEDICINE
- Study coordinator: LOPEZ-TERRADA, DOLORES
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.