Identifying risk factors for type 2 diabetes in adolescents

Identify risk factors for type 2 diabetes in adolescents

NIH-funded research Research Inst Nationwide Children's Hosp · NIH-11053343

This study is looking at what causes type 2 diabetes in kids aged 9 to 13, especially those who are overweight, to help figure out who might be at risk and how to prevent it.

Quick facts

Grant typeU01 cooperative agreement
Study typeNIH-funded research
Funding institutionResearch Inst Nationwide Children's Hosp NIH-funded
Lab location1 site (Columbus, United States)
Project IDNIH-11053343 on NIH RePORTER

What this research studies

This research investigates the risk factors that contribute to the development of type 2 diabetes (T2D) in adolescents, particularly focusing on those who are obese. The study will involve a cohort of 3,500 youth aged 9-13 years, assessing their insulin sensitivity, glucose levels, and other biological markers. By understanding the mechanisms behind T2D in this age group, the research aims to identify which adolescents are at higher risk and how to prevent the onset of this condition. Participants will be recruited from diverse urban and rural settings in Ohio, ensuring a comprehensive understanding of the factors involved.

Who could benefit from this research

Good fit: Ideal candidates for this research are adolescents aged 9-13 years who are classified as obese and have impaired fasting glucose or impaired glucose tolerance.

Not a fit: Patients who are not adolescents or do not have obesity or glucose intolerance may not benefit from this research.

Why it matters

Potential benefit: If successful, this research could lead to better identification and prevention strategies for type 2 diabetes in adolescents, ultimately improving their long-term health outcomes.

How similar studies have performed: Previous research has shown success in identifying risk factors for diabetes in adults, but this specific focus on adolescents is relatively novel.

Where this research is happening

Columbus, United States

Researchers

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page below.
Conditions adult onset diabetesAdult-Onset Diabetes Mellitus
Last reviewed 2026-06-13 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.