Identifying risk factors for epilepsy in children recovering from cerebral malaria
Predicting Epilepsy in Cerebral Malaria: Working Toward Identifying Biomarkers of Epileptogenesis in Children
This study is looking at how to tell which kids who have had cerebral malaria might develop epilepsy later on, so doctors can keep a closer eye on them and help them better, especially in places where resources are limited.
Quick facts
| Grant type | NIH-funded research |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Boston Children's Hospital NIH-funded |
| Lab location | 1 site (Boston, United States) |
| Project ID | NIH-10865073 on NIH RePORTER |
What this research studies
This research investigates how to predict which children who have suffered from cerebral malaria are at risk of developing epilepsy. By identifying specific clinical signs and EEG metrics, the study aims to create biomarkers that can help healthcare providers monitor these children more closely. This is particularly important in resource-limited settings where timely intervention can significantly impact outcomes. The research focuses on understanding the mechanisms behind epilepsy development following cerebral malaria, which could lead to better management strategies for affected children.
Who could benefit from this research
Good fit: Ideal candidates for this research are children aged 0-11 years who have recently recovered from cerebral malaria.
Not a fit: Patients who have not experienced cerebral malaria or are older than 11 years may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to improved monitoring and treatment strategies for children at risk of developing epilepsy after cerebral malaria.
How similar studies have performed: While research on epilepsy following cerebral malaria is limited, the approach of identifying biomarkers in a specific disease context has shown promise in other studies.
Where this research is happening
Boston, United States
- Boston Children's Hospital — Boston, United States (Active)
Researchers
- Principal investigator: Patel, Archana a. — Boston Children's Hospital
- Study coordinator: Patel, Archana a.
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.