Identifying proteins released by muscles during exercise
Official title: 3D micro-physiological systems for identification of therapeutic myokines
Funded at Emory University · NIH-11062435 · Data updated 2026-11-12
This study is looking at how muscles release special proteins called myokines that can affect other parts of the body, and it aims to learn more about how exercise influences these proteins to help improve health and find new treatment options.
Quick facts
| Grant type | R01 grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Emory University NIH-funded |
| Lab location | 1 site (Atlanta, United States) |
| Project start | May 22, 2023 |
| Project end | April 30, 2028 |
| Funding year | 2025 |
| Award (this year) | $449,686 |
| NIH project number | 5R01AR080169-03 |
| Project ID | NIH-11062435 on NIH RePORTER |
Who could benefit from this research
✓Could help
Ideal candidates for this research are individuals with conditions related to muscle function, such as adult-onset diabetes or cardiovascular issues.
✕Less likely to help
Patients with non-muscle related conditions or those who are unable to engage in physical activity may not benefit from this research.
What this research studies
This research focuses on understanding how skeletal muscles release specific proteins, known as myokines, that can influence other organs in the body. By using advanced 3D microengineering techniques, the researchers will create a model that mimics the muscle environment to study these proteins more effectively. They will also develop a system to track how exercise affects the release of these myokines, which could lead to new insights into the benefits of physical activity on overall health. The goal is to uncover novel myokines that could be targeted for therapeutic purposes.
Why it matters
Potential benefit: If successful, this research could lead to new treatments that harness the beneficial effects of exercise on various health conditions.
How similar studies have gone: Previous research has shown promise in understanding myokines and their effects, suggesting that this approach could yield valuable insights.
Where this research is happening
-
Emory University
Atlanta, United States Active
Researchers
- Principal investigator: Jang, Young Charles — Emory University
- Study coordinator: Jang, Young Charles
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About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page.