Identifying proteins linked to heart disease recurrence in heart attack survivors
Official title: Proteomic discovery in an inception cohort of acute myocardial infarction survivors
Funded at University of Washington · NIH-10676123 · Data updated 2026-11-12
This study is looking at why some people have repeated heart problems after a heart attack by checking proteins in their blood, and it hopes to find new ways to help prevent future heart issues for those who have survived a heart attack.
Quick facts
| Grant type | R01 grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | University of Washington NIH-funded |
| Lab location | 1 site (Seattle, United States) |
| Project start | August 15, 2020 |
| Project end | July 31, 2025 |
| Funding year | 2023 |
| Award (this year) | $693,268 |
| NIH project number | 5R01HL149706-04 |
| Project ID | NIH-10676123 on NIH RePORTER |
Who could benefit from this research
✓Could help
Ideal candidates for this research are individuals who have recently survived an acute myocardial infarction and are at risk for recurrent coronary heart disease.
✕Less likely to help
Patients who have not experienced a heart attack or those with advanced heart disease may not benefit from this research.
What this research studies
This research investigates the causes of recurrent coronary heart disease (CHD) in survivors of acute myocardial infarction by analyzing a large number of proteins in their blood. Using advanced proteomics techniques, the study aims to identify new protein biomarkers that could serve as potential therapeutic targets for preventing further heart issues. Participants will be monitored over a long period to assess the relationship between these proteins and the risk of experiencing additional heart problems. The study combines genetic data and clinical information to enhance understanding of heart disease recurrence.
Why it matters
Potential benefit: If successful, this research could lead to new treatments that significantly reduce the risk of recurrent heart disease in patients who have survived a heart attack.
How similar studies have gone: Previous research using proteomics has shown promise in identifying biomarkers for cardiovascular diseases, suggesting that this approach could yield valuable insights.
Where this research is happening
-
University of Washington
Seattle, United States Active
Researchers
- Principal investigator: Floyd, James S — University of Washington
- Study coordinator: Floyd, James S
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About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page.