Identifying proteins at the single-molecule level for better health insights
Single-molecule protein identification and single-cell proteomics
This study is working on a new way to find and understand proteins in tiny samples, like single cells or blood tests, which could help doctors get better information about diseases like COVID-19 and cancer, leading to more personalized and accurate treatments for patients.
Quick facts
| Grant type | NIH-funded research |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Rice University NIH-funded |
| Lab location | 1 site (Houston, United States) |
| Project ID | NIH-10899531 on NIH RePORTER |
What this research studies
This research focuses on developing a new technology to identify proteins from very small samples, such as single cells or liquid biopsies, without needing to amplify the proteins. By using advanced imaging techniques, the researchers aim to accurately detect and profile proteins, which are crucial for understanding cellular states and changes. This approach could lead to better biomarkers for diseases, including COVID-19 and cancers, enhancing precision medicine. Patients may benefit from more accurate diagnostics and personalized treatment options based on their unique protein profiles.
Who could benefit from this research
Good fit: Ideal candidates include individuals with conditions like COVID-19 or cancers, where precise protein profiling could significantly impact treatment decisions.
Not a fit: Patients with conditions that do not involve protein biomarkers or those who are not undergoing treatment that requires protein analysis may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to more accurate and personalized diagnostics and treatments for various diseases.
How similar studies have performed: While the approach of single-molecule protein identification is innovative, similar techniques in high-throughput proteomics have shown promise in other studies, suggesting potential for success.
Where this research is happening
Houston, United States
- Rice University — Houston, United States (Active)
Researchers
- Principal investigator: Dai, Mingjie — Rice University
- Study coordinator: Dai, Mingjie
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.