Identifying protein markers to understand and predict pancreatic cancer risk

Uncovering Causal Protein Markers to Characterize Pancreatic Cancer Etiology and Improve Risk Prediction

NIH-funded research University of Hawaii at Manoa · NIH-10946247

This study is looking at how certain proteins might contribute to pancreatic cancer, with the goal of helping patients understand their risk better and improving ways to detect the disease early.

Quick facts

Grant typeU01 cooperative agreement
Study typeNIH-funded research
Funding institutionUniversity of Hawaii at Manoa NIH-funded
Lab location1 site (Honolulu, United States)
Project IDNIH-10946247 on NIH RePORTER

What this research studies

This research focuses on pancreatic cancer, particularly pancreatic ductal adenocarcinoma, which is a leading cause of cancer death. It aims to uncover the causal role of specific proteins in the development of this cancer and improve risk prediction models. By utilizing advanced methodologies, including genetic instruments, the study seeks to address inconsistencies in previous findings related to protein biomarkers. Patients may benefit from enhanced screening strategies and better understanding of their risk factors for pancreatic cancer.

Who could benefit from this research

Good fit: Ideal candidates for this research include individuals at high risk for pancreatic cancer, such as those with a family history of the disease or specific genetic predispositions.

Not a fit: Patients with non-cancerous conditions or those without risk factors for pancreatic cancer may not receive any benefit from this research.

Why it matters

Potential benefit: If successful, this research could lead to more accurate risk assessments and improved screening methods for pancreatic cancer.

How similar studies have performed: Previous research has shown promise in identifying protein biomarkers for various cancers, suggesting that this approach could yield valuable insights for pancreatic cancer as well.

Where this research is happening

Honolulu, United States

Researchers

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page below.
Last reviewed 2026-06-10 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.