Identifying protein markers to understand and predict pancreatic cancer risk
Official title: Uncovering Causal Protein Markers to Characterize Pancreatic Cancer Etiology and Improve Risk Prediction
Funded at University of Hawaii at Manoa · NIH-10946247 · Data updated 2026-11-12
This study is looking at how certain proteins might contribute to pancreatic cancer, with the goal of helping patients understand their risk better and improving ways to detect the disease early.
Quick facts
| Grant type | U01 cooperative agreement |
|---|---|
| Study type | NIH-funded research |
| Funding institution | University of Hawaii at Manoa NIH-funded |
| Lab location | 1 site (Honolulu, United States) |
| Project start | September 18, 2024 |
| Project end | August 31, 2029 |
| Funding year | 2024 |
| Award (this year) | $737,444 |
| NIH project number | 1U01CA293883-01 |
| Project ID | NIH-10946247 on NIH RePORTER |
Who could benefit from this research
✓Could help
Ideal candidates for this research include individuals at high risk for pancreatic cancer, such as those with a family history of the disease or specific genetic predispositions.
✕Less likely to help
Patients with non-cancerous conditions or those without risk factors for pancreatic cancer may not receive any benefit from this research.
What this research studies
This research focuses on pancreatic cancer, particularly pancreatic ductal adenocarcinoma, which is a leading cause of cancer death. It aims to uncover the causal role of specific proteins in the development of this cancer and improve risk prediction models. By utilizing advanced methodologies, including genetic instruments, the study seeks to address inconsistencies in previous findings related to protein biomarkers. Patients may benefit from enhanced screening strategies and better understanding of their risk factors for pancreatic cancer.
Why it matters
Potential benefit: If successful, this research could lead to more accurate risk assessments and improved screening methods for pancreatic cancer.
How similar studies have gone: Previous research has shown promise in identifying protein biomarkers for various cancers, suggesting that this approach could yield valuable insights for pancreatic cancer as well.
Where this research is happening
-
University of Hawaii at Manoa
Honolulu, United States Active
Researchers
- Principal investigator: Wu, Lang — University of Hawaii at Manoa
- Study coordinator: Wu, Lang
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About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page.