Identifying protein markers to better understand and predict prostate cancer risk in Africans and Europeans
Uncovering causal protein markers to improve prostate cancer etiology understanding and risk prediction in Africans and Europeans
['FUNDING_R01'] · UNIVERSITY OF HAWAII AT MANOA · NIH-10896350
This study is looking at certain proteins to better understand how prostate cancer develops and to help predict who might be at higher risk, focusing on both African and European populations to find common markers that can improve screening and treatment for everyone.
Quick facts
| Phase | ['FUNDING_R01'] |
|---|---|
| Study type | Nih_funding |
| Sex | All |
| Sponsor | UNIVERSITY OF HAWAII AT MANOA (nih funded) |
| Locations | 1 site (HONOLULU, UNITED STATES) |
| Trial ID | NIH-10896350 on ClinicalTrials.gov |
What this research studies
This research investigates the role of specific proteins in the development of prostate cancer (PCa) to improve understanding of its causes and enhance risk prediction models. By focusing on both African and European populations, the study aims to identify which protein biomarkers are relevant across different ethnicities. The approach includes applying innovative study designs to overcome limitations found in previous research, such as selection bias. The ultimate goal is to develop more effective tools for predicting aggressive forms of PCa, which could lead to better screening and treatment strategies.
Who could benefit from this research
Good fit: Ideal candidates for this research include men of African and European descent who are at risk for prostate cancer.
Not a fit: Patients who do not have a family history of prostate cancer or those who are not of African or European descent may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to improved risk assessment and earlier detection of aggressive prostate cancer, potentially saving lives.
How similar studies have performed: While there have been studies on prostate cancer biomarkers, this research aims to address gaps in knowledge regarding ethnic differences, making it a novel approach.
Where this research is happening
HONOLULU, UNITED STATES
- UNIVERSITY OF HAWAII AT MANOA — HONOLULU, UNITED STATES (ACTIVE)
Researchers
- Principal investigator: WU, LANG — UNIVERSITY OF HAWAII AT MANOA
- Study coordinator: WU, LANG
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.