Identifying patients at risk of lung disease after tuberculosis treatment
Official title: Identifying patients at risk of post-tuberculosis lung disease using novel cough and adherence predictors
Funded at University of California, San Francisco · NIH-10891638 · Data updated 2026-11-12
This study is looking for ways to help people who have finished their tuberculosis treatment by finding out who might develop lung problems later on, using new tools like a mobile app to track coughs instead of just relying on standard lung tests.
Quick facts
| Grant type | Career grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | University of California, San Francisco NIH-funded |
| Lab location | 1 site (San Francisco, United States) |
| Project start | July 20, 2023 |
| Project end | July 31, 2028 |
| Funding year | 2024 |
| Award (this year) | $174,420 |
| NIH project number | 5K01HL165039-02 |
| Project ID | NIH-10891638 on NIH RePORTER |
Who could benefit from this research
✓Could help
Ideal candidates for this research are individuals who have recently completed treatment for tuberculosis and may be experiencing respiratory symptoms.
✕Less likely to help
Patients who have not been treated for tuberculosis or those with pre-existing chronic lung diseases unrelated to TB may not benefit from this research.
What this research studies
This research investigates how to identify patients who are at risk of developing post-tuberculosis lung disease (PTLD) after completing their TB treatment. It aims to use innovative methods, such as monitoring cough frequency and using a mobile app to analyze cough sounds, as alternatives to traditional lung function tests that may not be available in many regions. By understanding patient adherence to treatment and changes in cough patterns, the study seeks to improve early detection and intervention for those at risk of PTLD.
Why it matters
Potential benefit: If successful, this research could lead to better early identification and management of patients at risk for post-tuberculosis lung disease, potentially improving their long-term health outcomes.
How similar studies have gone: Other research has shown promise in using mobile health technologies for monitoring respiratory conditions, indicating that this approach may be effective.
Where this research is happening
-
University of California, San Francisco
San Francisco, United States Active
Researchers
- Principal investigator: Huddart, Sophie — University of California, San Francisco
- Study coordinator: Huddart, Sophie
Related research
Other NIH-funded projects on the same topics.
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Understanding how cough spreads tuberculosis
This study is looking at how coughing helps spread the bacteria that cause tuberculosis (TB) so we can find better ways to prevent and treat the disease, especially for those at higher risk.
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Understanding and preventing lung problems after tuberculosis treatment
This research aims to find new ways to identify people who are at risk of developing long-term lung issues after completing treatment for tuberculosis.
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Understanding how tuberculosis bacteria cause cough and spread
This study is looking at how the bacteria that cause tuberculosis can make people cough, which helps them spread the infection, and it aims to find out how this happens so we can better control the disease.
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Coronary disease and immune activation in people with HIV and tuberculosis coinfection
This research looks at how having HIV and latent tuberculosis together might raise the risk of heart disease, and what immune changes are involved.
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Pulmonary rehabilitation to reduce breathing problems after tuberculosis
A program of guided exercise and breathing training to help adults who have recovered from TB breathe better and feel healthier.
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Pulmonary rehab to reduce breathing troubles after TB
A program of pulmonary rehabilitation is being studied to help adults who have completed TB treatment avoid ongoing lung problems and improve daily breathing.
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page.