Identifying patients at risk for resistant hypertension and cardiovascular issues
Official title: Hypertension Prediction and Identification in All of Us
Funded at University of Florida · NIH-10924018 · Data updated 2026-11-12
This study is looking at data to help find out which people with high blood pressure might not respond to regular medications and are at risk for serious heart issues, so we can create better, personalized treatment plans to keep everyone healthier.
Quick facts
| Grant type | R03 grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | University of Florida NIH-funded |
| Lab location | 1 site (Gainesville, United States) |
| Project start | September 10, 2023 |
| Project end | August 31, 2025 |
| Funding year | 2024 |
| Award (this year) | $152,500 |
| NIH project number | 5R03HL172123-02 |
| Project ID | NIH-10924018 on NIH RePORTER |
Who could benefit from this research
✓Could help
Ideal candidates for this research are adults over 21 years old who are currently taking antihypertensive medications but still have uncontrolled blood pressure.
✕Less likely to help
Patients who do not have hypertension or are not currently on antihypertensive medications may not benefit from this research.
What this research studies
This research aims to analyze existing data from the All of Us Research Program to better identify patients with hypertension who are at risk for treatment-resistant hypertension and serious cardiovascular problems. By examining various factors that contribute to hypertension and its treatment, the study seeks to understand why some patients do not respond to standard blood pressure medications. The goal is to improve patient outcomes by tailoring treatment strategies based on individual risk profiles. This approach may help in recognizing those who need more intensive management to prevent severe health complications.
Why it matters
Potential benefit: If successful, this research could lead to more effective treatment strategies for patients with resistant hypertension, ultimately reducing the risk of heart attacks and strokes.
How similar studies have gone: Previous research has shown promise in using large datasets to identify patient risk factors for hypertension, indicating that this approach could yield valuable insights.
Where this research is happening
-
University of Florida
Gainesville, United States Active
Researchers
- Principal investigator: Mcdonough, Caitrin W — University of Florida
- Study coordinator: Mcdonough, Caitrin W
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About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page.