Identifying patients at high risk for stroke using advanced MRI techniques
Predicting Stroke Risk in Intracranial Atherosclerotic Disease with Novel High Resolution,Functional and Molecular MRI Techniques - Resubmission - 1
This study is looking to help people with a specific type of artery disease in the brain by using advanced MRI scans to find out who is most at risk for having another stroke, so they can get the best treatment tailored just for them.
Quick facts
| Grant type | R01 grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | University of Chicago NIH-funded |
| Lab location | 1 site (Chicago, United States) |
| Project ID | NIH-10687232 on NIH RePORTER |
What this research studies
This research aims to reduce the incidence of stroke by using advanced MRI scans to identify patients with intracranial atherosclerotic disease (ICAD) who are at the highest risk for recurrent strokes. The study will evaluate new MRI techniques that can detect vulnerable plaques and assess cerebrovascular reserve, which are critical for determining the best treatment options. By comparing these new imaging methods to established techniques, the research seeks to improve patient selection for interventions like angioplasty or new medications. Ultimately, this could lead to more personalized and effective management of stroke risk in patients with ICAD.
Who could benefit from this research
Good fit: Ideal candidates for this research are patients diagnosed with intracranial atherosclerotic disease who have experienced a stroke or are at high risk for stroke recurrence.
Not a fit: Patients with stroke risk factors unrelated to intracranial atherosclerosis or those who have not experienced a stroke may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could significantly lower the risk of recurrent strokes in vulnerable patients by enabling targeted treatment strategies.
How similar studies have performed: Previous research has shown promise in using advanced imaging techniques for stroke risk assessment, indicating that this approach could lead to meaningful advancements in patient care.
Where this research is happening
Chicago, United States
- University of Chicago — Chicago, United States (Active)
Researchers
- Principal investigator: Carroll, Timothy J — University of Chicago
- Study coordinator: Carroll, Timothy J
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.