Identifying pathogens in endocarditis directly from blood samples
Direct-from-specimen identification of pathogens common in endocarditis
['FUNDING_SBIR_2'] · HELIXBIND, INC. · NIH-11013411
This study is testing a new, quick test that can help doctors find infections in the heart faster and more accurately, so patients can get the right treatment sooner and spend less time in the hospital.
Quick facts
| Phase | ['FUNDING_SBIR_2'] |
|---|---|
| Study type | Nih_funding |
| Sex | All |
| Sponsor | HELIXBIND, INC. (nih funded) |
| Locations | 1 site (Boxborough, UNITED STATES) |
| Trial ID | NIH-11013411 on ClinicalTrials.gov |
What this research studies
This research focuses on improving the diagnosis of infective endocarditis, a serious condition caused by bacterial or fungal infections in the heart. It aims to develop a rapid, automated test called RaPID/IE that can identify these pathogens directly from blood samples in about three hours, eliminating the need for traditional culture methods that can take much longer and may yield false negatives. By providing faster and more accurate results, this approach seeks to enhance patient outcomes and reduce hospital stays.
Who could benefit from this research
Good fit: Ideal candidates for this research are patients suspected of having infective endocarditis, particularly those experiencing symptoms of bloodstream infections.
Not a fit: Patients who do not have infective endocarditis or those who are not experiencing symptoms of a bloodstream infection may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to quicker and more accurate diagnoses of infective endocarditis, improving treatment outcomes for patients.
How similar studies have performed: Other research has shown promise in developing rapid diagnostic tests for infections, indicating that this approach could be effective.
Where this research is happening
Boxborough, UNITED STATES
- HELIXBIND, INC. — Boxborough, UNITED STATES (ACTIVE)
Researchers
- Principal investigator: SINGER, ALON — HELIXBIND, INC.
- Study coordinator: SINGER, ALON
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.