Identifying non-coding RNA drivers of cancer
Unveiling non-coding drivers of cancer
This study is looking at how certain non-coding RNAs might affect cancer growth and treatment responses, with the goal of helping patients get more personalized care based on a deeper understanding of their cancer.
Quick facts
| Grant type | R01 grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | University of Chicago NIH-funded |
| Lab location | 1 site (Chicago, United States) |
| Project ID | NIH-10890007 on NIH RePORTER |
What this research studies
This research investigates the role of non-coding RNAs in cancer development and progression. By utilizing advanced genome sequencing technologies, the team aims to uncover how these non-coding RNAs can influence tumor behavior and response to treatment. The study will analyze large datasets from various cancer genome sequencing projects to identify novel non-coding RNA candidates that may serve as biomarkers or therapeutic targets. Patients may benefit from a better understanding of their cancer's molecular drivers, potentially leading to more personalized treatment options.
Who could benefit from this research
Good fit: Ideal candidates for this research include individuals diagnosed with various types of cancer, particularly those with unexplained tumor behavior or resistance to current therapies.
Not a fit: Patients with non-cancerous conditions or those whose cancers are well-understood and have established treatment protocols may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to new biomarkers and drug targets that improve cancer diagnosis and treatment.
How similar studies have performed: Previous research has shown promise in identifying non-coding RNAs as significant players in cancer biology, suggesting that this approach could yield valuable insights.
Where this research is happening
Chicago, United States
- University of Chicago — Chicago, United States (Active)
Researchers
- Principal investigator: Yang, Lixing — University of Chicago
- Study coordinator: Yang, Lixing
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.