Identifying new subtypes of irritable bowel syndrome using gut bacteria and metabolites.
A Systems Biology Approach Using Fecal Microbiota and Metabolomics to Identify Novel Subtypes in Irritable Bowel Syndrome.
This study is looking at how the bacteria in your gut and their byproducts can help us understand the different types of irritable bowel syndrome (IBS) and figure out which treatments might work best for you.
Quick facts
| Grant type | NIH-funded research |
|---|---|
| Study type | NIH-funded research |
| Funding institution | University of Michigan at Ann Arbor NIH-funded |
| Lab location | 1 site (Ann Arbor, United States) |
| Project ID | NIH-10579289 on NIH RePORTER |
What this research studies
This research investigates how the interactions between gut bacteria and metabolites can reveal different subtypes of irritable bowel syndrome (IBS). By analyzing fecal samples and using advanced statistical methods, the study aims to identify which patients are more likely to respond to specific treatments. The approach includes training in laboratory techniques and predictive analytics to enhance understanding of IBS. This could lead to more personalized treatment options for patients suffering from IBS.
Who could benefit from this research
Good fit: Ideal candidates for this research are individuals diagnosed with diarrhea-predominant irritable bowel syndrome (IBS-D).
Not a fit: Patients with other forms of irritable bowel syndrome or those without a diagnosis of IBS may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to more effective and tailored treatments for patients with irritable bowel syndrome.
How similar studies have performed: Other research has shown promise in using microbiota and metabolomics to understand gastrointestinal disorders, indicating potential for success in this approach.
Where this research is happening
Ann Arbor, United States
- University of Michigan at Ann Arbor — Ann Arbor, United States (Active)
Researchers
- Principal investigator: Lee, Allen a — University of Michigan at Ann Arbor
- Study coordinator: Lee, Allen a
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.