Identifying new biomarkers for gastric cancer risk using blood metabolites
Circulating metabolites as novel risk biomarkers for gastric cancer: a large multi-center prospective investigation
['FUNDING_R37'] · SLOAN-KETTERING INST CAN RESEARCH · NIH-10883354
This study is looking at how certain substances in the blood might help predict the risk of developing gastric cancer in people who have a Helicobacter pylori infection, and it aims to find easy ways to spot this risk without needing invasive tests.
Quick facts
| Phase | ['FUNDING_R37'] |
|---|---|
| Study type | Nih_funding |
| Sex | All |
| Sponsor | SLOAN-KETTERING INST CAN RESEARCH (nih funded) |
| Locations | 1 site (NEW YORK, UNITED STATES) |
| Trial ID | NIH-10883354 on ClinicalTrials.gov |
What this research studies
This research investigates the role of circulating metabolites as potential risk biomarkers for gastric cancer, particularly in individuals infected with Helicobacter pylori. By utilizing advanced metabolomics techniques, the study aims to identify non-invasive biomarkers that can help assess the risk of developing gastric cancer in high-risk populations. The research will involve a large multi-center prospective cohort, allowing for a comprehensive analysis of how various metabolites relate to gastric cancer risk. Patients will be monitored over time to gather data on their metabolite levels and cancer development.
Who could benefit from this research
Good fit: Ideal candidates for this research include individuals who are infected with Helicobacter pylori and are at risk for developing gastric cancer.
Not a fit: Patients who do not have Helicobacter pylori infection or those with other unrelated health conditions may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to improved screening and prevention strategies for gastric cancer, potentially saving lives through early detection.
How similar studies have performed: Previous studies have successfully identified risk biomarkers for other cancers using metabolomics, suggesting a promising avenue for gastric cancer as well.
Where this research is happening
NEW YORK, UNITED STATES
- SLOAN-KETTERING INST CAN RESEARCH — NEW YORK, UNITED STATES (ACTIVE)
Researchers
- Principal investigator: SHU, XIANG — SLOAN-KETTERING INST CAN RESEARCH
- Study coordinator: SHU, XIANG
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.