Identifying new biomarkers for diagnosing syphilis in pregnant women and evaluating treatment response
Multi-omic approaches to identify novel biomarkers for the diagnosis of syphilis in pregnancy and assessment of treatment response
This study is looking for better ways to diagnose syphilis in pregnant women by finding new markers in their biological samples, so they can get the right treatment quickly and help keep both moms and babies healthy.
Quick facts
| Grant type | R21 grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | University of California, San Francisco NIH-funded |
| Lab location | 1 site (San Francisco, United States) |
| Project ID | NIH-10979056 on NIH RePORTER |
What this research studies
This research focuses on improving the diagnosis of syphilis in pregnant women by using multi-omic approaches to identify novel biomarkers. It aims to address the challenges of current diagnostic tests that may not accurately distinguish between past and current infections. The study will analyze various biological samples to develop more effective diagnostic tools, which could lead to timely and appropriate treatment for pregnant women at risk of congenital syphilis. By enhancing diagnostic accuracy, the research seeks to improve maternal and infant health outcomes.
Who could benefit from this research
Good fit: Ideal candidates for this research are pregnant women who are at risk for syphilis or have been diagnosed with the infection.
Not a fit: Patients who are not pregnant or those who do not have a risk of syphilis infection may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to more accurate and timely diagnoses of syphilis in pregnancy, ultimately reducing the risk of serious complications for both mothers and infants.
How similar studies have performed: Previous research has shown promise in using multi-omic approaches for biomarker discovery, indicating potential for success in this novel application.
Where this research is happening
San Francisco, United States
- University of California, San Francisco — San Francisco, United States (Active)
Researchers
- Principal investigator: Gaw, Stephanie Lina — University of California, San Francisco
- Study coordinator: Gaw, Stephanie Lina
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.