Identifying MRI biomarkers for assessing dementia risk after stroke

Stroke Connectome MRI Biomarkers for VCID Risk Assessment

NIH-funded research University of Wisconsin-Madison · NIH-11079598

This study is looking at how brain scans can help us understand the risk of memory and thinking problems in people who have had a stroke, especially focusing on those from different backgrounds, to learn more about what affects brain health after a stroke.

Quick facts

Grant typeR01 grant
Study typeNIH-funded research
Funding institutionUniversity of Wisconsin-Madison NIH-funded
Lab location1 site (Madison, United States)
Project IDNIH-11079598 on NIH RePORTER

What this research studies

This research investigates how certain brain imaging biomarkers can help assess the risk of vascular contributions to cognitive impairments and dementia (VCID) in stroke survivors. By utilizing advanced MRI techniques and machine learning, the study aims to understand the interactions between socio-economic factors, brain health, and stroke-related changes. Participants, particularly from underrepresented groups, will be recruited to ensure diverse representation and to better understand the risk factors associated with VCID. The research seeks to fill gaps in current knowledge about how these factors contribute to cognitive decline after a stroke.

Who could benefit from this research

Good fit: Ideal candidates for this research include stroke survivors, particularly those from African American, Hispanic, and Native American backgrounds, who may be at higher risk for VCID.

Not a fit: Patients who have not experienced a stroke or do not have cognitive impairments related to vascular issues may not benefit from this research.

Why it matters

Potential benefit: If successful, this research could lead to improved methods for diagnosing and predicting dementia risk in stroke survivors, ultimately enhancing patient care.

How similar studies have performed: Previous research has shown promise in using MRI biomarkers to assess cognitive decline, suggesting that this approach may yield valuable insights.

Where this research is happening

Madison, United States

Researchers

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page below.
Conditions Alzheimer disease dementiaAlzheimer syndromeAlzheimer's Disease
Last reviewed 2026-06-13 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.