Identifying molecular markers for pulmonary sarcoidosis
Comprehensive Proteomic Classifier for the Molecular Characterization of Pulmonary Sarcoidosis
This study is looking to find ways to tell if pulmonary sarcoidosis will get worse or stay the same by checking proteins in blood and lung samples, which could help doctors give you the best treatment possible.
Quick facts
| Grant type | R01 grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | University of Minnesota NIH-funded |
| Lab location | 1 site (Minneapolis, United States) |
| Project ID | NIH-10907457 on NIH RePORTER |
What this research studies
This research aims to develop predictive models that can classify pulmonary sarcoidosis into progressive and non-progressive forms. By analyzing proteins in blood and lung samples, the team seeks to identify biomarkers that can help in diagnosing and determining the best treatment strategies for patients. The study involves a multidisciplinary approach, combining expertise in proteomics, immunology, and bioinformatics to understand the disease better. Ultimately, the goal is to improve patient outcomes by providing more targeted and effective treatment options.
Who could benefit from this research
Good fit: Ideal candidates for this research are individuals diagnosed with pulmonary sarcoidosis, particularly those experiencing symptoms of progressive disease.
Not a fit: Patients with sarcoidosis who are asymptomatic or have already received definitive treatment may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to more accurate diagnoses and personalized treatment plans for patients with pulmonary sarcoidosis.
How similar studies have performed: Previous research has shown promise in using proteomic approaches to identify biomarkers in other diseases, suggesting potential success for this novel approach in sarcoidosis.
Where this research is happening
Minneapolis, United States
- University of Minnesota — Minneapolis, United States (Active)
Researchers
- Principal investigator: Bhargava, Maneesh — University of Minnesota
- Study coordinator: Bhargava, Maneesh
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.