NIH-funded research R01 grant

Identifying molecular factors that predict heart events in chronic coronary artery disease

Official title: Molecular predictors of cardiovascular events and resilience in chronic coronary artery disease

Funded at New York University School of Medicine · NIH-11091643 · Data updated 2026-11-12

This study is looking for new ways to understand and predict heart problems in people with chronic coronary artery disease, so that doctors can tailor treatments to each person’s needs and help them live healthier lives.

More Resilience research and trials

Quick facts

Grant typeR01 grant
Study typeNIH-funded research
Funding institutionNew York University School of Medicine
NIH-funded
Lab location1 site (New York, United States)
Project startAugust 15, 2023
Project endMay 31, 2028
Funding year2025
Award (this year)$742,913
NIH project number5R01HL165208-03
Project IDNIH-11091643 on NIH RePORTER

Who could benefit from this research

Could help

Ideal candidates for this research include individuals diagnosed with chronic coronary artery disease who are at risk for cardiovascular events.

Less likely to help

Patients without chronic coronary artery disease or those who do not have risk factors for cardiovascular events may not benefit from this research.

What this research studies

This research investigates the molecular predictors of cardiovascular events and resilience in patients with chronic coronary artery disease (CAD). By utilizing a multi 'omics' approach, the study aims to uncover novel biomarkers that can better assess individual risk and resilience to CAD. This will help personalize treatment decisions and improve patient outcomes by addressing the residual risks that current assessments overlook. The research leverages data from landmark trials and a cohort study to ensure comprehensive analysis and validation of findings.

Why it matters

Potential benefit: If successful, this research could lead to more accurate risk assessments and personalized treatment strategies for patients with chronic coronary artery disease.

How similar studies have gone: Previous research has shown promise in using multi 'omics' approaches to identify biomarkers in cardiovascular diseases, suggesting potential for success in this novel investigation.

Where this research is happening

  • New York University School of Medicine
    New York, United States
    Active

Researchers

  • Principal investigator: Newman, Jonathan D — New York University School of Medicine
  • Study coordinator: Newman, Jonathan D

Related research

Other NIH-funded projects on the same topics.

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page.
Last reviewed 2026-11-14 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.