Identifying medications that may cause pancreatic injury
Determining medications associated with drug-induced pancreatic injury through novel pharmacoepidemiology techniques that assess causation
This study is looking into whether some medications might cause acute pancreatitis, a condition that can lead to serious hospital visits, and it's designed for anyone who wants to understand how their medications could affect their pancreas and overall health.
Quick facts
| Grant type | R01 grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | University of Pittsburgh at Pittsburgh NIH-funded |
| Lab location | 1 site (Pittsburgh, United States) |
| Project ID | NIH-11088122 on NIH RePORTER |
What this research studies
This research investigates the potential link between certain medications and acute pancreatitis, a condition that leads to significant hospitalizations. By utilizing advanced pharmacoepidemiology techniques and electronic health databases, the study aims to identify which medications may contribute to drug-induced pancreatic injury (DIPI). This approach allows for a comprehensive analysis of medication effects while considering various patient factors, ultimately aiming to improve patient safety and treatment outcomes.
Who could benefit from this research
Good fit: Ideal candidates for this research include individuals who have experienced acute pancreatitis or are at risk for the condition due to medication use.
Not a fit: Patients who have not experienced acute pancreatitis or are not taking medications that could potentially cause this condition may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could help identify safe medications for patients at risk of acute pancreatitis, reducing hospitalizations and improving quality of life.
How similar studies have performed: Previous research has shown success in identifying medication-related adverse effects using similar pharmacoepidemiological approaches, indicating the potential for meaningful findings in this study.
Where this research is happening
Pittsburgh, United States
- University of Pittsburgh at Pittsburgh — Pittsburgh, United States (Active)
Researchers
- Principal investigator: Vajravelu, Ravy Kuppalapalle — University of Pittsburgh at Pittsburgh
- Study coordinator: Vajravelu, Ravy Kuppalapalle
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.