Identifying markers to predict healing in leg ulcers

Developing biomarkers of healing and non-healing VLUs

NIH-funded research University of Miami School of Medicine · NIH-10786898

This study is looking at the fluid from old bandages to find clues that can help doctors know if Venous Leg Ulcers will heal, so they can give better treatments and improve healing, especially for older patients.

Quick facts

Grant typeR21 grant
Study typeNIH-funded research
Funding institutionUniversity of Miami School of Medicine NIH-funded
Lab location1 site (Coral Gables, United States)
Project IDNIH-10786898 on NIH RePORTER

What this research studies

This research focuses on analyzing wound fluid from discarded dressings to develop biomarkers that can predict whether Venous Leg Ulcers (VLUs) will heal. By studying the molecular changes in the wound environment, the project aims to identify key indicators that can help healthcare providers tailor treatments more effectively. This approach addresses the significant challenge of healing VLUs, particularly in an aging population where standard treatments often fail. The goal is to enhance patient outcomes by providing insights into the healing process and guiding therapy decisions.

Who could benefit from this research

Good fit: Ideal candidates for this research are individuals suffering from Venous Leg Ulcers, particularly those who have not responded well to standard treatments.

Not a fit: Patients with acute wounds or those not diagnosed with Venous Leg Ulcers may not benefit from this research.

Why it matters

Potential benefit: If successful, this research could lead to improved healing rates for patients with Venous Leg Ulcers, reducing the burden of chronic wounds.

How similar studies have performed: Previous research has shown promise in using biomarkers for wound healing, suggesting that this approach could yield valuable insights.

Where this research is happening

Coral Gables, United States

Researchers

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page below.
Last reviewed 2026-06-13 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.