Identifying markers to predict healing in leg ulcers
Official title: Developing biomarkers of healing and non-healing VLUs
Funded at University of Miami School of Medicine · NIH-10786898 · Data updated 2026-11-12
This study is looking at the fluid from old bandages to find clues that can help doctors know if Venous Leg Ulcers will heal, so they can give better treatments and improve healing, especially for older patients.
Quick facts
| Grant type | R21 grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | University of Miami School of Medicine NIH-funded |
| Lab location | 1 site (Coral Gables, United States) |
| Project start | September 18, 2023 |
| Project end | August 31, 2025 |
| Funding year | 2023 |
| Award (this year) | $371,470 |
| NIH project number | 1R21AR083526-01 |
| Project ID | NIH-10786898 on NIH RePORTER |
Who could benefit from this research
✓Could help
Ideal candidates for this research are individuals suffering from Venous Leg Ulcers, particularly those who have not responded well to standard treatments.
✕Less likely to help
Patients with acute wounds or those not diagnosed with Venous Leg Ulcers may not benefit from this research.
What this research studies
This research focuses on analyzing wound fluid from discarded dressings to develop biomarkers that can predict whether Venous Leg Ulcers (VLUs) will heal. By studying the molecular changes in the wound environment, the project aims to identify key indicators that can help healthcare providers tailor treatments more effectively. This approach addresses the significant challenge of healing VLUs, particularly in an aging population where standard treatments often fail. The goal is to enhance patient outcomes by providing insights into the healing process and guiding therapy decisions.
Why it matters
Potential benefit: If successful, this research could lead to improved healing rates for patients with Venous Leg Ulcers, reducing the burden of chronic wounds.
How similar studies have gone: Previous research has shown promise in using biomarkers for wound healing, suggesting that this approach could yield valuable insights.
Where this research is happening
-
University of Miami School of Medicine
Coral Gables, United States Active
Researchers
- Principal investigator: Jozic, Ivan — University of Miami School of Medicine
- Study coordinator: Jozic, Ivan
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About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page.