Identifying key regulators of immune cell development and function
Systems-level identification of key regulators deciding immune cell state
This study is looking at how immune cells grow and change, using advanced technology to understand what controls their behavior, and it’s for anyone interested in finding new ways to improve treatments for immune-related conditions.
Quick facts
| Grant type | R01 grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | University of California, San Diego NIH-funded |
| Lab location | 1 site (La Jolla, United States) |
| Project ID | NIH-10816492 on NIH RePORTER |
What this research studies
This research investigates how immune cells develop and differentiate by identifying the key regulators involved in these processes. Using advanced genomic technologies, the team will analyze various immune cell populations to uncover the regulatory mechanisms that dictate immune cell behavior. The study employs a novel systems biology approach to integrate complex multiomics data, allowing for a comprehensive understanding of immune system regulation. By comparing human and mouse immune cells, the research aims to reveal conserved mechanisms that could inform new therapeutic strategies.
Who could benefit from this research
Good fit: Ideal candidates for this research include individuals with autoimmune conditions or cancers who may benefit from novel immunomodulatory therapies.
Not a fit: Patients with stable immune conditions or those not affected by autoimmune diseases or cancers may not receive direct benefits from this research.
Why it matters
Potential benefit: If successful, this research could lead to the development of more effective treatments for autoimmune diseases and cancers by targeting specific regulators of immune cell function.
How similar studies have performed: Other research has shown success in using systems biology approaches to understand immune regulation, indicating that this methodology has potential for impactful findings.
Where this research is happening
La Jolla, United States
- University of California, San Diego — La Jolla, United States (Active)
Researchers
- Principal investigator: Wang, Wei — University of California, San Diego
- Study coordinator: Wang, Wei
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.