Identifying key regions in HIV that lead to new virus strains.
Official title: A novel approach to pinpoint predisposed recombination regions in HIV for a global profile of HIV recombinants' occurrence and evolution
Funded at Triad National Security, LLC · NIH-10850807 · Data updated 2026-11-12
This study is looking at how different strains of HIV mix together and aims to help public health officials make better decisions, which could lead to improved treatments and vaccines for people living with HIV.
Quick facts
| Grant type | R21 grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Triad National Security, LLC NIH-funded |
| Lab location | 1 site (Los Alamos, UNITED STATES) |
| Project start | June 1, 2023 |
| Project end | May 31, 2026 |
| Funding year | 2024 |
| Award (this year) | $197,008 |
| NIH project number | 7R21AI176947-02 |
| Project ID | NIH-10850807 on NIH RePORTER |
Who could benefit from this research
✓Could help
Ideal candidates for this research include individuals living with HIV or those at high risk of HIV infection.
✕Less likely to help
Patients who are not infected with HIV or are not at risk of HIV infection may not benefit from this research.
What this research studies
This research aims to understand how HIV recombination events occur and to predict emerging recombinant clusters that can inform public health decisions. By addressing flaws in the current classification system for HIV recombinant families, the study seeks to gather comprehensive data on HIV's evolution and recombination. The approach involves analyzing genetic information to pinpoint regions of the HIV genome that are predisposed to recombination, which could enhance surveillance and the development of targeted treatments. Patients may benefit from improved public health strategies and more effective vaccines or antiviral therapies as a result of this research.
Why it matters
Potential benefit: If successful, this research could lead to better public health strategies and more effective treatments for HIV.
How similar studies have gone: Other research has shown success in understanding HIV evolution and recombination, but this approach aims to provide a novel and comprehensive global profile.
Where this research is happening
-
Triad National Security, LLC
Los Alamos, United States Active
Researchers
- Principal investigator: Zhang, Ming — Triad National Security, LLC
- Study coordinator: Zhang, Ming
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page.